derived allele frequency
2019-06-30 本文已影响1人
YX_Andrew
A DAF of 95% could be due to:
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chance, alleles will fix or be weeded out by chance especially if your effective population size is low. Chimps have a greater effective population size but could still fix or weed out variants by chance.
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positive selection
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weak background selection
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error in the inferred allele for the chimp/human. It also implies that there was a single allele back then. It's possible that the one fixed in humans and the other in chimps by pure chance.