DNA 转座子概况

文章：DNA Transposons and the Evolution of Eukaryotic Genomes

文章地址：http://europepmc.org/article/PMC/2167627#free-full-text

文章内容

Eukaryotic DNA transposons can be divided into three major subclasses: (i) those those that excise as double-stranded DNA and reinsert elsewhere in the genome, i.e., the classic “cut-and-paste” transposons (35); (ii) those that utilize a mechanism probably related to rolling-circle replication, Helitrons (91); and (iii) Mavericks, whose mechanism of transposition is not yet well understood, but that likely replicate using a self-encoded DNA polymerase (160). Both Helitronsand Mavericks most likely rely on distinct transposition mechanisms involving the displacement and replication of a single-stranded DNA intermediate, respectively. Thus these elements probably transpose through a replicative, copy-and-paste process.