my summary

1.The biggest difference between a Licensed Vocational Nurse (LVN) and a Licensed Practical Nurse (LPN) is actually the name.  The term LVN is used in California and Texas, while LPN is used throughout the rest of the United States.  So the difference in title really just depends on where you are.

2. Typically the followup period is 14 days for a drug study and 42 days for a live, attenuated viral vaccine study.

3. drug ineffective: Felt drug ineffective for headache----Drug ineffective for unapproved indication;

was presribed with Livial for headache and hot feeling all over---Intentional use for unlabelled indication

was prescribed with half tablet of Livial-----Drug prescribing error

unlabelled indications were improved after taking Livial----Unexpected therapeutic drug effect