Pharmacokinetic VS Pharmacodynam
2021-12-21 本文已影响0人
林書鈺
The pharmacokinetic(藥物(代謝)動力學) is the study of how the body effect a drug?
It can be through the absorption吸收, distribution分配,Metabolism代謝,以及elimination排出 to talk about the drug in body.
The pharmacodynamics (藥效學)is the study of the effects of a drug on the body and in particular the interaction of drug on the receptor that is targeted site of action.
(1) Receptor mechanisms(受體機制): receptors are channels on cells that act as gate keepers of brain communication
(2) Dose-response curve (劑量反應曲線)
(3) Therapeutic index治療指數--> relative measure of the safety and toxicity of drug .
(4) Tolerance, (耐受性) dependence(依賴性) and withdrawal symptoms(戒斷反應)
