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2024-01-11 本文已影响0人
LET149
10.15252/msb.20209596
doi: 10.1002/wrna.1325
The limitation of ribosomal biogenesis will extend the lifespan and healthspan.
https://doi.org/10.1126/science.adg0934
- Ribosomal subunits proteins decrease along aging
- Cell type specific aging/features
- Aging is different between sexes (sexual dimorphism)
- Within the same tissues, cell composition change along aging
- Within the same tissues, different cell types contribute differently to the aging of this tissue
- The nucleus number of fat-body cells increase along aging, fay-body of Drosophila is a liver-like tissue which is account for storing fat and
serves as a detoxifying and immune-responsive tissue