染色体臂的相关知识

2023-05-21  本文已影响0人  xiaosine
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Each human chromosome has a short arm ("p" for "petit") and long arm ("q" for "queue"), separated by a centromere. The ends of the chromosome are called telomeres.

Each chromosome arm is divided into regions, or cytogenetic bands, that can be seen using a microscope and special stains. The cytogenetic bands are labeled p1, p2, p3, q1, q2, q3, etc., counting from the centromere out toward the telomeres. At higher resolutions, sub-bands can be seen within the bands. The sub-bands are also numbered from the centromere out toward the telomere.

For example, the cytogenetic map location of the CFTR gene is 7q31.2, which indicates it is on chromosome 7, q arm, band 3, sub-band 1, and sub-sub-band 2.
The ends of the chromosomes are labeled ptel and qtel. For example, the notation 7qtel refers to the end of the long arm of chromosome 7.

如何获取小鼠的染色体臂坐标
https://hgdownload.soe.ucsc.edu/goldenPath/mm10/database/cytoBand.txt.gz

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