全基因组关联分析流程(三)
2018-02-28 本文已影响114人
正踪大米饭儿
拿到结果后,我们对结果进行展示,一般 GWAS 的标准结果图为 曼哈顿图 和 QQ 图,作图代码如下:
## 加载作图包
library(qqman)
## 添加候选 SNP 标记位点显示
candidate_Gene <- c("SYN2040", "SYN25096",
"SYN6161","PZE-108000718",
"SYN28779","PZE-108000725","SYN25098",
"PHM7953.11","SYN10050",
"SYN35436","SYN28782",
"SYN25094","SYN17706",
"PZE-109109509", "PZE-109109408",
"PZE-107060597", "PZE-107061311",
"PZE-105106278", "PZE-104065772"
)
YN <- read.table("YN_Adjust.txt", header = T)
manhattan(WJ2, main = "Manhattan Plot",
ylim = c(0, 10), cex = 0.6,
cex.axis = 0.9,
col = c("blue4", "orange3"),
suggestiveline = F, genomewideline = 4.6,
# chrlabs = c(1:10),
highlight = candidate_Gene
)
qq(WJ2$P, main = "Q-Q plot of GWAS p-values",
xlim = c(0, 6), ylim = c(0, 9), pch = 18,
col = "blue4", cex = 1.1, las = 1
)
曼哈顿图
QQ 图
数据示例入下:
作图数据示例
END