fasterq-dump解压的一些细节

平时也没怎么关注fasterq-dump解压缩的细节，随便搜一下网上的教程解压就行
也就是一般是下面的这个命令

fasterq-dump --split-3  -e 20 *.sra

但是我发现这样实际上是调用不到多线程的？但是有时任务不急就没管，不过现在要弄接近一百个文件，每个解压缩后都很大，所以不得不看帮助文档了

Usage: fasterq-dump [ options ] [ accessions(s)... ]

Parameters:

  accessions(s)                    list of accessions to process


Options:

  -o|--outfile <path>              full path of outputfile (overrides usage
                                     of current directory and given accession)
  -O|--outdir <path>               path for outputfile (overrides usage of
                                     current directory, but uses given
                                     accession)
  -b|--bufsize <size>              size of file-buffer (dflt=1MB, takes
                                     number or number and unit)
  -c|--curcache <size>             size of cursor-cache (dflt=10MB, takes
                                     number or number and unit)
  -m|--mem <size>                  memory limit for sorting (dflt=100MB,
                                     takes number or number and unit)
  -t|--temp <path>                 path to directory for temp. files
                                     (dflt=current dir.)
  -e|--threads <count>             how many threads to use (dflt=6)
  -p|--progress                    show progress (not possible if stdout used)
  -x|--details                     print details of all options selected
  -s|--split-spot                  split spots into reads
  -S|--split-files                 write reads into different files
  -3|--split-3                     writes single reads into special file
     --concatenate-reads           writes whole spots into one file
  -Z|--stdout                      print output to stdout
  -f|--force                       force overwrite of existing file(s)
  -N|--rowid-as-name               use rowid as name (avoids using the name
                                     column)
     --skip-technical              skip technical reads
     --include-technical           explicitly include technical reads
  -P|--print-read-nr               include read-number in defline
  -M|--min-read-len <count>        filter by sequence-lenght
     --table <name>                which seq-table to use in case of pacbio
     --strict                      terminate on invalid read
  -B|--bases <bases>               filter output by matching against given
                                     bases
  -A|--append                      append to output-file, instead of
                                     overwriting it
     --ngc <path>                  <path> to ngc file
     --perm <path>                 <path> to permission file
     --location <location>         location in cloud
     --cart <path>                 <path> to cart file
     --disable-multithreading      disable multithreading
  -V|--version                     Display the version of the program
  -L|--log-level <level>           Logging level as number or enum string.
                                     One of
                                     (fatal|sys|int|err|warn|info|debug) or
                                     (0-6) Current/default is warn
     --option-file file            Read more options and parameters from the
                                     file.
  -h|--help                        print this message

version 2.10.7

所以很容易看明白为何速度就是上不去，因为内存和缓存限制，需要改这些参数才行，不能用默认的(有服务器的才这么搞，本地就算了）

fasterq-dump -e 30 -3 -b 100MB -c 200MB -m 2000MB *sra