Gene edits to ‘CRISPR babies’ mi

去年在朋友圈引发热议的基因编辑双胞胎女孩，最近研究结果显示CCR5基因缺失可能导致其寿命缩短。Study of almost half a million people links mutation that protects against HIV infection to an earlier death.

Sara Reardon

The scientist who edited the genomes of

twin girls in an attempt to make them

resistant to HIV might have inadvertently

shortened their life expectancy.

People with two disabled copies of the CCR 5 gene — the version that protects against

HIV infection — are 21% more likely to die

before the age of 76 than are people with at least one working copy of the gene, according to a study 1 published on 3 June in

Nature Medicine. The reason for the

discrepancy is unknown.