3500个TNBC单细胞转录组数据重处理
2019-04-23 本文已影响58人
因地制宜的生信达人
文章:A Targetable EGFR-Dependent Tumor-Initiating Program in Breast Cancer , 因为bulk测序无法解决问题,所以作者选择了单细胞转录组测序策略:
To understand functional properties associated with heterogeneous EGFR expression in an unbiased manner, single cell RNA-seq was performed on freshly dissociated cells from the PDX (3,483 cells, with an average of 40,564 unique molecular identifiers (UMIs) and 5,146 genes detected per cell)
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