Motif
2018-07-21 本文已影响10人
翠湖心影
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Sequence motif, a sequence pattern of nucleotides in a DNA sequence or amino acids in a protein
Structural motif, a pattern in a protein structure formed by the spatial arrangement of amino acids
Short linear motif, a stretch of protein sequence that mediates protein–protein interaction
chip-seq motif discovery:
通过motif预测DNA上可能会有哪些转录因子结合。每个转录因子都有一个DNA结合结构域(DBD),喜欢结合在特定DNA序列上,也就是motif。如果我感兴趣的基因上游DNA有某个TF的motif,那么该TF就有可能结合这段DNA,从而调控下游基因表达。