SNPedia.com网站公布的10个最火热的snp

你遇到了吗？

SNPedia是一个调查人类遗传学的维基百科，引用同行评议的科学出版物，共享有关DNA变异影响的信息。 SNPedia博客刚刚(2009年)发布了网站上访问的10个最受欢迎的SNP列表。

SNPedia现在包含近10,000个SNP，为了迎接2010年，我们希望突出至少10个。这些SNP是基于医学重要性，统计可信度和整体一般兴趣的难以捉摸的且最终主观的组合选择的。尽管这不是客观的科学，但可以随意评论一下为什么你最喜欢的SNP应该列出来。

列表如下：

1. rs4244285: SNP in the CYP2C19 gene related to the antiplatelet drug clopidogrel.
2. rs4149056: Determining risk for statin-triggered myopathy.
3. rs1799853, rs1057910 & rs8050894: These SNPs in the CYP2C9 & VKORC1 genes help determine the optimal dose of the anticoagulant drug warfarin.
4. rs10757278: Risk for coronary artery disease and it’s consequences (like heart attacks).
5. rs1537415: Risk for periodontitis.
6. rs3892097: This SNP encodes the CYP2D6*4 allele determining poorer outcome among breast cancer patients treated with tamoxifen
7. rs1447295: Risk for prostate cancer.
8. gs138, gs139, gs140: Represent the rapid, intermediate, and slow metabolizers for the detoxifying enzyme NAT2.
9. rs17646946 & rs11803731: Hair curliness.
10. rs2395029: A variety of conditions (like psoriasis, abacavir hypersensitivity) plus liver damage among patients taking the antibiotic flucloxacillin.

如今已经到了2017年的尾声，你们知道SNPedia发生了什么故事吗？

敬请期待~~~

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