写好Response letter，让editor啧啧称赞

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论文投出去也只是paper路上的第一站，等上两三个月，看到不是rejection，而是revision，不论是major还是minor都是一件值得高兴的事情。

但是需要对着审稿人的comments来修改，response 也是个磨人的小妖精。

今天我们就为大家来策一策，怎么足够有礼有节清晰明了进退自如地写response letter~

首先上基本原则：

（1）有礼有节：避免针锋相对，对comments有则改之无则加勉

对方提的意见比较好——感谢审稿人，我们已经做出对应修改

对方很明显没有看懂——可能是我们写作不够清晰，为了避免读者有类似误解，稍作修改

对方纯属找茬——我们在文章的第几部分，cite了什么文献，已经说明了对应问题

（2）直击重点：在对应的reply里面做出有理有据的解释，不要试图摸鱼，但也不要直接暴露缺点

比如审稿人提出，需要补充实验，可以补充的列出实验结果。不可以补充的，表达作者充分认识到这个实验有所帮助，但目前条件不允许，未来可以针对开展，这次的话我们已经增加了相应的文献，可以帮助支撑论点

（3）清晰明了：尽可能节省审稿人和编辑的阅读时间，哪些地方做了哪些修改，都在response letter里面依次列出

Comments按照顺序排列，comments和response采用不同颜色或斜体字体以区分

文章中的修改使用蓝色/红色/黄色字体，使审稿人和编辑可以一目了然看到修改

Response里面对于增添的内容可以稍作介绍，如 （added to page 11-12：添加的内容或图表），（添加的内容， Ref.23）

说了这么多，你可能还是想看看具体的实例吧

首先是general response，大意是感谢一下编辑和审稿人，他们提的意见真的非常有用——我们根据意见做了很详尽的修改因此文章质量也大幅提升了呢——然后说明一下，下文是我们详细的“点对点”修改

例一

例二

然后用一个标题：Response to comments on “文章题目（编号）”

Reviewer #1 (Remarks to the Author) 

Reviewer #2 (Remarks to the Author)

同样和对审稿人1号的回复一样，依次列出

再来看一看常见句式：

1. 论文语言太差，需要润色

（1）We tried our best to improve the manuscript and made some changes in the manuscript. These changes will not influence the content and framework of the paper. And here we did not list the changes but marked in red in revised paper. We appreciate for Editors/Reviewers’ warm work earnestly, and hope that the correction will meet with approval.

（2）Thanks for your suggestion. We have tried our best to polish the language in the revised manuscript.

2. 需要增加参考文献

（1）We sincerely appreciate the valuable comments. We have checked the literatures carefully and added more references on ___ and___ into the INTRODUCTION part in the revised manuscript.

参考文献1，参考文献2

（2）As suggested by the reviewer, we have added more references to support this idea (参考文献).

3. 表述不清，表格里面需要放更多数据或突出某些重点

Done, as requested. Tables 1 and 5 now include association results between eQTL and gene expression in breast tissue (based on GTEx V7). We have also added results for GTEx blood for comparison.

4. 需要补充实验的

1

可以补充且结果理想的

We have investigated ___ by using ___ . The main findings are presented in Figure 2 and reveals  ___ .The manuscript has been revised accordingly to clarify the above concerns.

2

补充了实验但结果不理想

As suggested by the referee, we have tried our best to verify ____by____. However, no positive results has been observed. 引用文献说明为啥结果不理想，

Other researchers also found that it is very difficult to obtain. As suggested in the literatures, ____

3

目前没有条件进行补充

We agree that more study would be useful to understand details of ____. At this point we do not have the necessary tool-set to study the ___. We hope, in the future, to employ ___ techniques to determine ___. （首先阐述没有客观条件）This study is beyond the scope of this report which focuses on answering critical questions regarding the ___.（第二步，阐述即使不补充这个实验也不影响文章阐述核心内容） We note also that since submission of our manuscript there has been a publication by  ___  showing that ___ (插入参考文献). We have added this citation and reference to the manuscript.（最后引用别的文献进行支撑）

以上只是一些共性的常见问题，但不同主题的paper写response letter可能会遇到不同的问题，如果可以找到已发表的同类型期刊文章的response相信对大家更有帮助，所以小编在此向大家安利Nature Communications，在它文章的sections中找到supplementary information，里面通常都会放上“Peer review file”里面就是审稿人的comments和对应的response 

回复“response letter”，可以下载小编为你准备的两个Nature Communications的response letter，分别是

1. 乳腺癌的GWAS分析（Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer）

2. RNA测序和生信分析发现癌症融合基因（Diagnosis of fusion genes using targeted RNA sequencing）

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