2018-12-17
2018-12-17 本文已影响0人
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| items | AlzRisk | polygenicpathways | append |
|---|---|---|---|
| Updated | 24 January 2018 | Last modified December 20, 2016 | |
| Risk Factor | Alcohol, B Vitamins, Blood Pressure, Cognitive Activity, Diabetes Mellitus, Dietary Pattern, Head injury, Homocysteine, Hormone Therapy, Inflammatory Biomarkers, Non-Steroidal Anti-Inflammatory Drugs, Nutritional Antioxidants, Obesity, Physical Activity, Statin use | Bold part:the genes and risk factors can be related. Age, Aluminium, Aluminium antidote,anaemia, Head injury, occupational exposure, Organic solvent, Exposure to air pollution(Immune-system and related), A longer duration of being breastfed, Hypertension, low frequency magnetic fields, smoking, cancer (Cell cycle and DNA Repair), Atherosclerosis, etc. | |
| Environmental | Infectious(4 places), Pathogens detected in the Alzheimer's disease brain, Dietary and lifestyle factors(7 places), Hormonal effects, Autoantibodies present in Alzheimer's disease sera, Epidemiological studies, Protective Drugs, Diets Vitamins and Vaccines(2 places), Biomarkers | ||
| the genes and risk factors can be related | Table 1: Components of the cholesterol shuttle and cholesterol and lipoprotein related genes that have been associated with Alzheimer's disease. Table 2. Growth factors and growth factor signalling. Table 3 Nuclear receptors and transcription factors associated with Alzheimer's disease. Table 4: Oxidative stress genes. Table 5: Proteases and protease inhibitors and activators associated with Alzheime's disease. Genes involved in glucose metabolism, acetyl CoA shuttling and acetylcholine metabolism associated with Alzheimer's disease. Cholinergic receptors. Table 7: Monoamine related genes associated with Alzheime's disease. Table 8 Immune-system and related. Table 9 Miscellaneous genes associated with Alzheimer's disease. |
| items | AlzGene | append |
|---|---|---|
| Updated | 18 April 2011 | |
| Studies | 1395 | |
| Genes | 695 | |
| Polymorphisms | 2973 | |
| Meta-analyses | 320 | |
| search | Chromosome, Gene, Protein, Polymorphism, Study |
