B细胞亚型及其Marker
2020-05-30 本文已影响0人
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| B Cell Type | Marker | Cellular localization |
|---|---|---|
| B cell (all except plasma cell) | IgM, CD19 | Secreted |
| Activated B cell | CD19, CD25, CD30 | Secreted |
| Plasma cell | IgG, CD27, CD38, CD78, CD138, CD319 | Secreted |
| Plasma cell | IL-6 | Secreted (cytokine) |
| Plasma cell | CD138 | Cell membrane |
| Memory cell | IgA, IgG, IgE, CD20, CD27, CD40, CD80, PDL-2 | Secreted |
| Memory cell | CXCR3, CXCR4, CXCR5, CXCR6 | Secreted (chemokines) |
| Marginal zone B cells | CD1, CD21, CD27 | Secreted |
| Marginal zone B cells | Notch2 | Cell membrane |
| Follicular B cells | IgD, CD21, CD22, CD23 | Secreted |
| Regulatory B cells | IgD, CD1, CD5, CD21, CD24, TLR4 | Secreted |
| Regulatory B cells | IL-10, TGFβ | Secreted (cytokines) |
https://www.abcam.com/primary-antibodies/b-cells-basic-immunophenotyping
